BD Biosciences/APC Mouse Anti-Human CD11b/5 μL/340937,BD Biosciences,,BD Biosciences,bdbiosciences,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：BD Biosciences/APC Mouse Anti-Human CD11b/5 μL/340937

产品编号：340937

市场价：¥0.00

场地：美国(厂家直采)

产品分类：蛋白类>多肽>多肽合成>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：待定

品牌： BD Biosciences

公司：BD Biosciences,Inc.

公司分类：

商品介绍

Product DetailsRecommended AssayReferences

Description

CD11b, clone D12, is derived from hybridization of mouse NS-1 myeloma cells with spleen cells from BALB/c mice immunized with peripheral blood T lymphocytes.

CD11b recognizes a human leucocyte antigen that is the C3bi complement receptor (CR₃). CD11b is specific for the Mr 165-kilodalton (kd) α subunit of the CD11b/CD18 antigen heterodimer. The Mr 95-kd CD18 antigen, the β chain of leucocyte function–associated antigen-1 (LFA-1β), is common to the CD11a/CD18 (LFA-1) and CD11c/CD18 antigen heterodimers.

Format

FormatAPC
Excitation SourceRed 633 nm
Excitation Max650nm
Emission Max660nm

Allophycocyanin (APC), is an accessory photosynthetic pigment found in blue-green algae. Its molecular weight is approximately 105 kDa. APC has six phycocyanobilin chromophores per molecule, which makes it a very bright fluorochrome that is highly suitable for flow cytometry applications. Due to nearly identical excitation and emission properties but different spillover characteristics, APC and Alexa Fluor® 647 cannot be used simultaneously

Resources & Tools
Spectrum Viewer	Panel Designer	SpectrumViewer	Download MSDS	Download TDS

Preparation and Storage

The monoclonal antibody is supplied as 100 µg puriﬁed immunoglobulin in 2.0 mL (50 µg/mL) of phosphate-buffered saline (PBS). The PE conjugate is supplied as 100 µg in 2.0 mL (50 µg/mL). The APC conjugate is supplied as 25 µg in 0.5 mL (50 µg/mL). PBS contains gelatin and 0.1% sodium azide.

Store vials at 2° to 8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

Bernstein ID, Self S. Joint report of the myeloid section of the Second International Workshop on Human Leukocyte Differentiation Antigens. In: Reinherz EL, Haynes BF, Nadler LM, Bernstein ID, eds. Leukocyte Typing II: Human Myeloid and Hematopoietic Cells. New York, NY: Springer-Verlag; 1986;3:1-25.
Bray R, Gottschalk L, Landay A, Gebel H. Differential surface marker expression in patients with CD16⁺ lymphoproliferative disorders: In vivo model for NK differentiation. Human Immunol. 1987;19:105.
Clement LT, Grossi CE, Gartland FL. Morphologic and phenotypic features of the subpopulation of Leu- 2⁺ cells which suppress T cell proliferative responses. Human Immunol. 1984;131:2757.
Gebel HM, Kaizer H, Landay AL. Characterization of circulating suppressor T lymphocytes in bone marrow transplant recipients. Transplantation. 1987;43:258.
Landay A, Gartland L, Clement LT. Characterization of a phenotypically distinct subpopulation of Leu-2⁺ cells which suppress T cell proliferative responses. J Immunol. 1983;131:2757.
Lanier LL, Phillips JH. A map of the cell surface antigens expressed on resting and activated human natural killer cells. In: Reinherz EL, Haynes BF, Nadler LM, Bernstein ID, eds. Leukocyte Typing II: Human Myeloid and Hematopoietic Cells. New York, NY: Springer-Verlag; 1986;3:157-170.
Patarroyo M, Makgoba MW. Leucocyte adhesion to cells: molecular basis, physiological relevance, and abnormalities. Scand J Immunol. 1989;30:129-164.
Repo H, Jansson S-E, Leirisalo-Repo M. Anticoagulant selection influences flow cytometric determination of CD11b upregulation in vivo and ex vivo. J Immunol. 1995;185:65-79.
Ross GD, Cain JA, Lachmann PJ. Membrane complement receptor type three (CR₃) has lectinlike properties analogous to bovine conglutinin and functions as a receptor for zymosan and rabbit erythrocytes as well as a receptor for iC3b. J Immunol. 1985;134:3307.
Shalekoff S, Page-Shipp L, Tiemessen CT. Effects of anticoagulants and temperature on expression of activation markers CD11b and HLA-DR on human leukocytes. Clin Diagn Lab Immunol. 1998;5:695-702

品牌介绍

BD是世界上最大的生产和销售医疗设备、医疗系统和试剂的医疗技术公司之一。致力于提高全世界人类的健康水平。BD专注于改进药物治疗，提高传染性疾病诊断的质量和速度，推进新型药物和疫苗的研究与发现。公司于1897年在纽约成立，总部位于美国新泽西州的富兰克林湖，业务可分为BD医疗、BD诊断、BD生物科学三大类，生产销售包括医用耗材、实验室仪器、抗体、试剂、诊断等产品。

公司介绍

更多...

产品分类

更多...