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℡ 4000-520-616
℡ 4000-520-616
BD Biosciences/FITC Mouse Anti-Human CD10/20 μL/347503
产品编号:347503
市  场 价:¥9480.87
场      地:美国(厂家直采)
产品分类: 蛋白类>多肽>多肽合成>
联系QQ:1570468124
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美  元  价:$451.47
品      牌: BD Biosciences
公      司:BD Biosciences,Inc.
公司分类:
BD Biosciences/FITC Mouse Anti-Human CD10/20 μL/347503
商品介绍
Product DetailsRecommended AssayReferences

Description

The CD10 antibody, clone W8E7, is derived from the hybridization of P3-X63-Ag8.653 mouse myeloma cells with spleen cells of BALB/c mice immunized with blasts from a patient with non-T ALL.

The CD10 antibody (Anti-CALLA) recognizes a human common acute lymphoblastic leukemia antigen (CALLA), with a molecular weight of 100 kilodaltons (kDa). The CD10 antigen is identical to human membrane–associated neutral endopeptidase (NEP; EC 3.3.24.11), also known as enkephalinase.

Preparation and Storage

Store vials at 2°C–8°C. Conjugated forms should not be frozen. Protect from exposure to light. Each reagent is stable until the expiration date shown on the bottle label when stored as directed.

  1. Protection of Laboratory Workers from Occupationally Acquired Infections; Approved Guideline— Third Edition. Wayne, PA: Clinical and Laboratory Standards Institute; 2005. CLSI document M29-A3.

  2. Centers for Disease Control. Perspectives in disease prevention and health promotion update: universal precautions for prevention of transmission of human immunodeficiency virus, hepatitis B virus, and other bloodborne pathogens in health-care settings.MMWR. 1988;37:377-388.

  3. Dworzak MN, Fritsch G, Fleischer C, et al. Multiparameter phenotype mapping of normal and post-chemotherapy B lymphopoiesis in pediatric bone marrow. Leukemia. 1997;11:1266-1273.

  4. Dworzak MN, Fritsch G, Fröschl G, Printz D, Gadner H. Four-color flow cytometric investigation of terminal deoxynucleotidyl transferase–positive lymphoid precursors in pediatric bone marrow: CD79a expression precedes CD19 in early B-cell ontogeny. Blood. 1998;92:3203-3209.

  5. Greaves MF. Monoclonal antibodies as probes for leukemic heterogeneity and hematopoietic differentiation. In: Knapp W, ed. Leukemia Markers. New York, NY: Academic Press; 82,5548611111111

  6. Hann IM, Richards SM, Eden OB, Hill FGH. Analysis of the immunophenotype of children treated on the Medical Research Council United Kingdom Acute Lymphoblastic Leukaemia Trial XI (MRC UKALLXI). Leukemia. 1998;12:1249-1255.

  7. Le Bien TW, McCormack RT. The common acute lymphoblastic leukemia antigen (CD10): emancipation from a functional enigma. Blood. 1989;73:625-635.

  8. Letarte M, Vera S, Tran R, et al. Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase. J Exp Med. 1988;168:1247-1253.

  9. Loken MR, Shah VO, Dattilio KL, Civin CI. Flow cytometric analysis of human bone marrow. II. Normal B-lymphocyte development. Blood. 1987;70:1316-1324.

  10. Nadler LM, Korsmeyer SJ, Anderson KC, et al. B cell origin of non-T cell acute lymphoblastic leukemia: a model for discrete stages of neoplastic and normal pre-B cell differentiation. J Clin Invest. 1984;74:332-340.

  11. Zola H. CD10 Workshop Panel report. In: Schlossman SF, Boumsell L, Gilks W, et al, eds. Leucocyte Typing V: White Cell Differentiation Antigens. New York, NY: Oxford University Press; 1995:505-507.

品牌介绍

BD是世界上最大的生产和销售医疗设备、医疗系统和试剂的医疗技术公司之一。致力于提高全世界人类的健康水平。BD专注于改进药物治疗,提高传染性疾病诊断的质量和速度,推进新型药物和疫苗的研究与发现。公司于1897年在纽约成立,总部位于美国新泽西州的富兰克林湖,业务可分为BD医疗、BD诊断、BD生物科学三大类,生产销售包括医用耗材、实验室仪器、抗体、试剂、诊断等产品。

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