BD Biosciences/Purified Mouse Anti-Human CD8/20 μL/346310,BD Biosciences,,BD Biosciences,bdbiosciences,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：BD Biosciences/Purified Mouse Anti-Human CD8/20 μL/346310

产品编号：346310

市场价：¥12461.40

场地：美国(厂家直采)

产品分类：蛋白类>多肽>多肽合成>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$593.40

品牌： BD Biosciences

公司：BD Biosciences,Inc.

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商品介绍

Product DetailsRecommended AssayReferences

Description

CD8 clone SK1 is derived from hybridization of mouse NS-1 myeloma cells with spleen cells from BALB/c mice immunized with human peripheral blood T lymphocytes.

The CD8 antibody recognizes the 32-kilodalton (kDa) α-subunit of a disulfide-linked bimolecular complex. The majority of peripheral blood CD8⁺ T lymphocytesexpress an α/β heterodimer (Mr 32, 30 kDa), while CD8⁺CD16⁺ natural killer (NK)lymphocytes and CD8⁺ T-cell receptor (TCR)-γ/δ⁺ T lymphocytes express an α/α homodimer (Mr 30 kDa). CD8⁺TCR-α/β⁺ T lymphocytes can express either an α/α homodimer or α/β heterodimer. The CD8 antigenic determinant binds to class I major histocompatibility (MHC) molecules, resulting in increased adhesion between the CD8+ T lymphocytes and target cells. Binding of the CD8 antigen to class I MHC molecules enhances the activation of resting T lymphocytes. The CD8 antigen is coupled to a protein tyrosine kinase, p56^lck. The CD8:p56^lck complex can play a role in T-lymphocyte activation through mediation of the interactions between the CD8 antigen and the CD3/TCR complex.

Format

FormatPurified

Other Formats→

APC
APC-Cy™7

APC-H7
AmCyan

FITC
PE-Cy™7

PerCP
PerCP-Cy™5.5

Resources & Tools
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Preparation and Storage

Store vials at 2°C to 8°C. Conjugated forms should not be frozen. Protect from exposure to light. Each reagent is stable until the expiration date shown on the bottle label when stored as directed.

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