BD Biosciences/Anti-Human CD4 FITC/CD38 PE/CD3 PerCP/HLA-DR APC/20 µL/340573,BD Biosciences,,BD Biosciences,bdbiosciences,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：BD Biosciences/Anti-Human CD4 FITC/CD38 PE/CD3 PerCP/HLA-DR APC/20 µL/340573

产品编号：340573

市场价：¥0.00

场地：美国(厂家直采)

产品分类：蛋白类>多肽>多肽合成>

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邮箱： info@ebiomall.com

美元价：待定

品牌： BD Biosciences

公司：BD Biosciences,Inc.

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商品介绍

Product DetailsRecommended AssayReferences

Description

CD4, clone SK3, is derived from hybridization of mouse NS-1 myeloma cells with spleen cells from BALB/c mice immunized with human peripheral blood T lymphocytes.

CD38, clone HB7, is derived from hybridization of mouse P3-X63-Ag8.653 myeloma cells with spleen cells from BALB/c mice immunized with the BJAB cell line.

CD3, clone SK7, is derived from hybridization of mouse NS-1 myeloma cells with spleen cells from BALB/c mice immunized with human thymocytes.

Anti–HLA-DR, clone L243, is derived from the hybridization of mouse NS-1/1-Ag4 myeloma cells with spleen cells from BALB/c mice immunized with the human lymphoblastoid B-cell line RPMI 8866.

CD4 recognizes an antigen that interacts with class II molecules of the major histocompatibility complex (MHC) and is the primary receptor for the human immunodeﬁciency virus. The cytoplasmic portion of the antigen is associated with the protein tyrosine kinase p56^lck. The CD4 antigen can regulate the function of the CD3 antigen/Tcell antigen receptor (TCR) complex. CD4 also reacts with monocytes/macrophages that have an antigen density lower than that on helper/inducer T lymphocytes.

CD38 recognizes an integral membrane glycoprotein, Mr 45 kDalton (kDa), with a protein core of 35 kDa.

CD3 recognizes the epsilon chain of the CD3 antigen/T-cell antigen receptor (TCR) complex. This complex is composed of at least six proteins that range in molecular weight from 20 to 30 kDa. The antigen recognized by the CD3 antibody is noncovalently associated with either α/β or γ/δ TCR (70 to 90 kDa).

Anti–HLA-DR recognizes a human class II MHC antigen. The antigen is a transmembrane glycoprotein composed of α and β subunits that have molecular weights of 36 and 27 kDa, respectively. Anti–HLA-DR reacts with a nonpolymorphic HLA-DR epitope and does not cross-react with HLA-DQ or HLA-DP molecules.

Specificity	Clone	Format	Isotype	Entrez Gene ID
HLA-DR	L243	APC	IgG_2a, κ	0
CD4	SK3 (also known as Leu3a)	FITC	IgG₁, κ	920
CD38	HB7 (also known as HB-7)	PE	IgG₁, κ	952
CD3	SK7 (also known as Leu-4)	PerCP	IgG₁, κ	916

Resources & Tools
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Preparation and Storage

The MultiTEST reagent is supplied as a combination of CD4 FITC, CD38 PE, CD3 PerCP, and Anti–HLA-DR APC in 1.0 mL of PBS containing bovine serum albumin, and 0.1% sodium azide. Vials should be stored at 2° to 8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

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